Substance: Isotretinoin
Manufacturer: Beligas Pharmaceuticals
Pack: 50 tabs (20mg/tab)

What is Isotretinoin?

Isotretinoin (brand name Accutane) is a powerful oral retinoid primarily used to treat severe acne. It works by shrinking oil glands and reducing skin inflammation.

Benefits for Bodybuilders:

Eliminates steroid-induced acne (common with Testosterone/Trenbolone)
Reduces oily skin (lowers sebum production by 90%)
Prevents cystic acne (deep, painful breakouts from androgens)

Usage Protocol:

• Standard Dose: 0.5-1mg/kg bodyweight daily (e.g., 40-80mg/day for 80kg users)

• Cycle Length: 4-6 months (cumulative dose determines long-term remission)

• Best Taken With: Fatty meal (increases absorption by 60%)

Potential Side Effects:

Severe dryness (lips, eyes, nasal passages)
Elevated liver enzymes (requires monthly blood tests)
Depression/mood changes (controversial but documented)
Photosensitivity (higher sunburn risk)

Who Should Avoid It?

Pregnant women (high risk of birth defects)
Those with liver/kidney disease
Patients with history of depression
People on tetracycline antibiotics

Bodybuilding-Specific Notes:

• Synergistic with steroids but may worsen joint pain (combine with omega-3s)

• Avoid vitamin A supplements (risk of hypervitaminosis)

• Bloodwork required (monitor triglycerides/LFTs monthly)